| S6906 |
Capric acid |
Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. |
Selective |
|
| S0165 |
Ampalex (CX-516) |
Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
Selective |
|
| S2860 |
IEM 1754 2HBr |
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM. |
Selective |
GluR1, IC50: 6 μM; GluR3, IC50: 6 μM |
| S6804 |
CX546 |
CX546, a prototypical ampakine agent, is a selective positive AMPA receptor modulator. |
Selective |
|
| S9686 |
NBQX (FG9202) |
NBQX (FG9202, NNC 079202) is a highly selective and competitive antagonist of AMPA receptor (AMPAR) with anti-epileptic effect. |
Selective |
|
| S4716 |
Evans Blue |
Evans Blue (Direct Blue 53,C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist. |
Selective |
|
| S2434 |
IDRA-21 |
IDRA-21 is a partial allosteric modulator of AMPA receptor desensitization. IDRA-21 is a potent cognition-enhancing drug virtually devoid of neurotoxic liability. |
Selective |
|
| S3070 |
Piracetam |
Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. |
Selective |
|
